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Nico van Rooijen Selected Research

Clodronic Acid (Clodronate)

1/2018Macrophages in bone fracture healing: Their essential role in endochondral ossification.
12/2015Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke.
12/2014Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.
10/2014Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma.
10/2014Effects of an immunomodulatory therapy and chondroitinase after spinal cord hemisection injury.
1/2014Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection.
12/2013Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.
3/2013Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction.
11/2012CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation.
8/2012Depletion and reconstitution of macrophages in mice.
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Nico van Rooijen Research Topics

Disease

53Inflammation (Inflammations)
01/2021 - 01/2002
51Infections
01/2018 - 12/2002
34Neoplasms (Cancer)
03/2015 - 01/2002
8Pneumonia (Pneumonitis)
01/2019 - 03/2005
8Peritonitis
11/2009 - 04/2002
7Fibrosis (Cirrhosis)
07/2015 - 07/2009
6Colitis
01/2018 - 10/2006
6Insulin Resistance
12/2013 - 01/2010
5Virus Diseases (Viral Diseases)
01/2018 - 05/2009
5Lymphoma (Lymphomas)
03/2015 - 02/2006
5Ischemia
03/2011 - 12/2005
4Vesicular Stomatitis
01/2018 - 11/2005
4Infarction (Infarctions)
12/2015 - 04/2008
4Stroke (Strokes)
12/2015 - 12/2011
4Hypoxia (Hypoxemia)
04/2014 - 10/2007
4Fatty Liver
12/2013 - 10/2007
4Atherosclerosis
05/2012 - 12/2010
4Hypertension (High Blood Pressure)
01/2011 - 01/2008
4Autoimmune Diseases (Autoimmune Disease)
12/2010 - 11/2006
3Ischemic Stroke
12/2015 - 06/2012
3Shock
12/2014 - 07/2003
3Sepsis (Septicemia)
12/2014 - 01/2005
3Spinal Cord Injuries (Spinal Cord Injury)
10/2014 - 02/2002
3Neoplasm Metastasis (Metastasis)
08/2013 - 11/2007
3Wounds and Injuries (Trauma)
03/2013 - 06/2009
3Necrosis
03/2013 - 05/2010
3Cholestasis
02/2013 - 01/2005
3Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2012 - 10/2008
3Lung Injury
09/2012 - 01/2009
3Acute Lung Injury
09/2012 - 05/2009
3B-Cell Lymphoma (Lymphoma, B Cell)
09/2012 - 02/2006
3Obesity
12/2010 - 11/2009
3Keratitis
03/2010 - 09/2007
3Hyperplasia
03/2010 - 04/2004
3Listeriosis (Listeria Infection)
09/2009 - 01/2002
3Glioma (Gliomas)
12/2008 - 01/2002

Drug/Important Bio-Agent (IBA)

52Clodronic Acid (Clodronate)IBA
01/2018 - 01/2002
42Liposomes (Liposome)IBA
01/2018 - 01/2002
39CytokinesIBA
06/2015 - 01/2002
13Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 01/2002
13Proteins (Proteins, Gene)FDA Link
01/2013 - 04/2004
10AntigensIBA
07/2015 - 01/2002
10ChemokinesIBA
06/2015 - 11/2005
9Interleukin-12 (IL 12)IBA
01/2013 - 07/2003
8Interleukin-10 (Interleukin 10)IBA
12/2014 - 01/2002
8Messenger RNA (mRNA)IBA
01/2013 - 10/2008
7Monoclonal AntibodiesIBA
01/2015 - 12/2005
7Complement System Proteins (Complement)IBA
09/2012 - 04/2004
6LipopolysaccharidesIBA
04/2020 - 07/2003
6Matrix Metalloproteinases (MMPs)IBA
03/2015 - 07/2006
6Interleukin-4 (Interleukin 4)IBA
01/2014 - 12/2005
6EnzymesIBA
11/2013 - 05/2002
6AutoantibodiesIBA
10/2012 - 02/2002
6LigandsIBA
09/2012 - 03/2005
6ZymosanIBA
06/2010 - 04/2002
5sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2018 - 04/2007
5Dextrans (Dextran)FDA Link
01/2018 - 04/2007
5Interferon Type IIBA
01/2018 - 12/2008
5LipidsIBA
04/2014 - 11/2008
5Insulin (Novolin)FDA Link
12/2013 - 11/2009
5ProstaglandinsIBA
10/2012 - 04/2002
5IntegrinsIBA
10/2012 - 04/2006
5Interleukin-6 (Interleukin 6)IBA
04/2012 - 12/2005
4InterleukinsIBA
02/2016 - 01/2010
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014 - 11/2007
4Glucose (Dextrose)FDA LinkGeneric
01/2014 - 09/2010
4Immunoglobulin G (IgG)IBA
08/2013 - 02/2007
4VaccinesIBA
12/2012 - 12/2007
4CollagenIBA
07/2012 - 07/2009
4Chemokine ReceptorsIBA
06/2012 - 01/2007
4Transforming Growth Factor beta (TGF-beta)IBA
01/2011 - 04/2004
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2011 - 02/2005
4Immunoglobulin M (IgM)IBA
12/2010 - 11/2005
4Nitric Oxide Synthase (NO Synthase)IBA
06/2010 - 05/2002
4Interferon-gamma (Interferon, gamma)IBA
01/2010 - 12/2005
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
04/2020 - 09/2012
3Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2018 - 02/2007
3Interleukin-1 (Interleukin 1)IBA
01/2018 - 12/2005
3Bleomycin (Blenoxane)FDA LinkGeneric
01/2018 - 01/2011
3Interleukin-18 (Interleukin 18)IBA
01/2017 - 12/2007
3Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
04/2014 - 12/2005
3EndotoxinsIBA
03/2014 - 10/2007
3Interleukin-13IBA
01/2014 - 07/2008
3Retinaldehyde (Retinal)IBA
01/2014 - 06/2004
3Insulin-Like Growth Factor I (IGF-1)IBA
01/2014 - 10/2007
3Antiviral Agents (Antivirals)IBA
11/2013 - 11/2011
3DNA (Deoxyribonucleic Acid)IBA
06/2013 - 12/2008
3Pharmaceutical PreparationsIBA
03/2013 - 02/2009
3InflammasomesIBA
02/2013 - 12/2010
3Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2013 - 04/2003
3Antigen-Antibody Complex (Immune Complex)IBA
10/2012 - 03/2005
3Rituximab (Mabthera)FDA Link
09/2012 - 02/2006
3OligodeoxyribonucleotidesIBA
09/2012 - 07/2009
3Monocyte Chemoattractant ProteinsIBA
06/2012 - 08/2007
3Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2011 - 01/2002
3Diphosphonates (Bisphosphonates)IBA
04/2004 - 01/2003

Therapy/Procedure

25Therapeutics
01/2021 - 01/2002
3Lasers (Laser)
03/2015 - 08/2003
3Intraperitoneal Injections
06/2013 - 01/2010
3Injections
03/2013 - 05/2003